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1

Differential induction of cytochrome P450 gene expression by 4n-alkyl-methylenedioxybenzenes in primary rat hepatocyte cultures

Jaspreet S. Sidhu, Craig B. Marcus, Andrew Parkinson, Curtis J. Omiecinski

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

1998

Language:

english

File:

PDF, 222 KB

english, 1998

2

Insulin-mediated modulation of cytochrome P450 gene induction profiles in primary rat hepatocyte cultures

Jaspreet S. Sidhu, Curtis J. Omiecinski

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

1999

Language:

english

File:

PDF, 181 KB

english, 1999

3

Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver

Rushang D. Patel, Brett D. Hollingshead, Curtis J. Omiecinski, Gary H. Perdew

Journal:

Year:

2007

Language:

english

File:

PDF, 299 KB

english, 2007

4

Comparison of genomic and cDNA sequences of guinea pig CYP2B18 and rat CYP2B2: Absence of a phenobarbital-responsive enhancer module in the upstream region of the CYP2B18 gene

Midori Yamamoto, Masashi Mise, Sanae Matsumoto, Shoich Ito, Noriko Gohyama, Satoru Ishida, Yasuhiro Sagara, Curtis J. Omiecinski, Kazuta Oguri, Hideyuki Yamada

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2004

Language:

english

File:

PDF, 216 KB

english, 2004

5

Absence of enantioselectivity in the pharmacodynamics of P450 2B induction by 5-ethyl-5-phenylhydantoin in the male rat liver or in cultured rat hepatocytes

Dr. Raymond W. Nims, Jaspreet S. Sidhu, Paul E. Thomas, Donna W. Mellini, Victor C. Nelson, Curtis J. Omiecinski, Ronald A. Lubet

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

1994

Language:

english

File:

PDF, 1007 KB

english, 1994

6

Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix

Erin G. Schuetz, Donna Li, Curtis J. Omiecinski, Ursula Muller-Eberhard, Hynda K. Kleinman, Barbara Elswick, Philip S. Guzelian

Journal:

Journal of Cellular Physiology

Year:

1988

Language:

english

File:

PDF, 2.03 MB

english, 1988

7

Bioassay-directed fractionation for discovery of bioactive neutral lipids guided by relative mass defect filtering and multiplexed collision-induced dissociation

Michael C. Stagliano, Joshua G. DeKeyser, Curtis J. Omiecinski, A. Daniel Jones

Journal:

Rapid Communications in Mass Spectrometry

Year:

2010

Language:

english

File:

PDF, 322 KB

english, 2010

8

The molecular basis of the human serum paraoxonase activity polymorphism

Humbert, Richard, Adler, David A., Disteche, Christine M., Hassett, Christopher, Omiecinski, Curtis J., Furlong, Clement E.

Journal:

Nature Genetics

Year:

1993

File:

PDF, 457 KB

1993

9

Functional analysis of human microsomal epoxide hydrolase genetic variants

Vinayak P. Hosagrahara, Allan E. Rettie, Christopher Hassett, Curtis J. Omiecinski

Journal:

Chemico-Biological Interactions

Year:

2004

Language:

english

File:

PDF, 152 KB

english, 2004

10

Preservation of hepatic phenotype in lentiviral-transduced primary human hepatocytes

Stephanie M. Zamule, Stephen C. Strom, Curtis J. Omiecinski

Journal:

Chemico-Biological Interactions

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

11

Differentiation of human embryonic stem cells along a hepatic lineage

Stephanie M. Zamule, Denise M. Coslo, Fengming Chen, Curtis J. Omiecinski

Journal:

Chemico-Biological Interactions

Year:

2011

Language:

english

File:

PDF, 2.10 MB

english, 2011

12

Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues

Katy M. Olsavsky, Jeanine L. Page, Mary C. Johnson, Helmut Zarbl, Stephen C. Strom, Curtis J. Omiecinski

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 2.45 MB

english, 2007

13

Expression profiling of interindividual variability following xenobiotic exposures in primary human hepatocyte cultures

Katy M.O. Goyak, Mary C. Johnson, Stephen C. Strom, Curtis J. Omiecinski

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 807 KB

english, 2008

14

Naphthalene metabolism in relation to target tissue anatomy, physiology, cytotoxicity and tumorigenic mechanism of action

Kenneth T. Bogen, Janet M. Benson, Garold S. Yost, John B. Morris, Alan R. Dahl, Harvey J. Clewell III, Kannan Krishnan, Curtis J. Omiecinski

Journal:

Regulatory Toxicology and Pharmacology

Year:

2008

Language:

english

File:

PDF, 329 KB

english, 2008

15

Lack of modulation by phenobarbital of cyclic AMP levels or protein kinase A activity in rat primary hepatocytes

Nancy B Beck, Curtis J Omiecinski

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 293 KB

english, 1999

16

Epoxide hydrolases: biochemistry and molecular biology

Adrian J Fretland, Curtis J Omiecinski

Journal:

Chemico-Biological Interactions

Year:

2000

Language:

english

File:

PDF, 125 KB

english, 2000

17

A large insertion in the Shiga-like toxin 2 gene (stx2) of an Escherichia coli O157:H7 clinical isolate

Karen C Jinneman, Stephen D Weagant, Janelle M Johnson, Sharon L Abbott, Walter E Hill, Bradley J Tenge, Ngoc-Lan Dang, Richard Ramsden, Curtis J Omiecinski

Journal:

International Journal of Food Microbiology

Year:

2000

Language:

english

File:

PDF, 332 KB

english, 2000

18

A Universal Approach to the Expression of Human and Rabbit Cytochrome P450s of the 2C Subfamily inEscherichia coli

Toby H. Richardson, Frank Jung, Keith J. Griffin, Mike Wester, Judy L. Raucy, Byron Kemper, Lester M. Bornheim, Christopher Hassett, Curtis J. Omiecinski, Eric F. Johnson

Journal:

Archives of Biochemistry and Biophysics

Year:

1995

Language:

english

File:

PDF, 164 KB

english, 1995

19

Human Hepatic Microsomal Epoxide Hydrolase: Comparative Analysis of Polymorphic Expression

Christopher Hassett, Jing Lin, Cara L. Carty, Elizabeth M. Laurenzana, Curtis J. Omiecinski

Journal:

Archives of Biochemistry and Biophysics

Year:

1997

Language:

english

File:

PDF, 711 KB

english, 1997

20

The Human Microsomal Epoxide Hydrolase Gene (EPHX1): Complete Nucleotide Sequence and Structural Characterization

Christopher Hassett, Kirsten B. Robinson, Nancy B. Beck, Curtis J. Omiecinski

Journal:

Year:

1994

File:

PDF, 639 KB

1994

21

Molecular induction by phenobarbital of a rat hepatic form of cytochrome P-450: Expression of a 4-kilobase messenger RNA

Curtis J. Omiecinski, Ronald N. Hines, Robert L. Foldes, Joan B. Levy, Edward Bresnick

Journal:

Archives of Biochemistry and Biophysics

Year:

1983

Language:

english

File:

PDF, 8.64 MB

english, 1983

22

Rabbit microsomal epoxide hydrolase: Isolation and characterization of the xenobiotic metabolizing enzyme cDNA

Christopher Hassett, Susan M. Turnblom, Audree DeAngeles, Curtis J. Omiecinski

Journal:

Archives of Biochemistry and Biophysics

Year:

1989

Language:

english

File:

PDF, 1.25 MB

english, 1989

23

Selective induction of cytochrome P450 isozymes in rat liver by 4-n-alkyl-methylenedioxybenzenes

Craig B. Marcus, Neil M. Wilson, Colin R. Jefcoate, Christopher F. Wilkinson, Curtis J. Omiecinski

Journal:

Archives of Biochemistry and Biophysics

Year:

1990

Language:

english

File:

PDF, 1.30 MB

english, 1990

24

Selective expression of cytochrome P450 isozymes by 4-n-alkyl-methylenedioxybenzenes in rat lung cells

Craig B. Marcus, Neil M. Wilson, Ingegerd M. Keith, Colin R. Jefcoate, Curtis J. Omiecinski

Journal:

Archives of Biochemistry and Biophysics

Year:

1990

Language:

english

File:

PDF, 4.24 MB

english, 1990

25

Use of a conserved consensus oligomer in the identification of cytochrome P-450 mRNAs

Christopher Hassett, Curtis J. Omiecinski

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 1.18 MB

english, 1987

26

Kinetics, activation, and induction of aortic mono-oxygenases—biotransformation of benzo[a]pyrene

James A. Bond, Curtis J. Omiecinski, Mont R. Juchau

Journal:

Biochemical Pharmacology

Year:

1979

Language:

english

File:

PDF, 757 KB

english, 1979

27

Substrate and position specificity of hematin-activated monooxygenation reactions

Curtis J. Omiecinski, Moses J. Namkung, Mont R. Juchau

Journal:

Biochemical Pharmacology

Year:

1981

Language:

english

File:

PDF, 1.02 MB

english, 1981

28

Regulation of the human cathepsin E gene by the constitutive androstane receptor

Jeanine L. Page, Stephen C. Strom, Curtis J. Omiecinski

Journal:

Archives of Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 551 KB

english, 2007

29

Phenobarbital responsiveness as a uniquely sensitive indicator of hepatocyte differentiation status: requirement of dexamethasone and extracellular matrix in establishing the functional integrity of cultured primary rat hepatocytes

Jaspreet S Sidhu, Fei Liu, Curtis J Omiecinski

Journal:

Experimental Cell Research

Year:

2004

Language:

english

File:

PDF, 1.01 MB

english, 2004

30

Phenobarbital responsiveness conferred by the 5′-flanking region of the rat CYP2B2 gene in transgenic mice

Richard Ramsden, Nancy B Beck, Karen M Sommer, Curtis J Omiecinski

Journal:

Year:

1999

Language:

english

File:

PDF, 452 KB

english, 1999

31

Xenobiotic microsomal epoxide hydrolase: 5′ sequence of the human gene

Neil M. Wilson, Curtis J. Omiecinski

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1989

Language:

english

File:

PDF, 318 KB

english, 1989

32

Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration

Takeda, Shuso, Okajima, Shunsuke, Miyoshi, Hiroko, Yoshida, Kazutaka, Okamoto, Yoshiko, Okada, Tomoko, Amamoto, Toshiaki, Watanabe, Kazuhito, Omiecinski, Curtis J., Aramaki, Hironori

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 863 KB

english, 2012

33

Effects of Chemical Inducers on Human Microsomal Epoxide Hydrolase in Primary Hepatocyte Cultures

Christopher Hassett, Elizabeth M Laurenzana, Jaspreet S Sidhu, Curtis J Omiecinski

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 1001 KB

english, 1998

34

Epoxide hydrolase — polymorphism and role in toxicology

Curtis J Omiecinski, Christopher Hassett, Vinayak Hosagrahara

Journal:

Toxicology Letters

Year:

2000

Language:

english

File:

PDF, 93 KB

english, 2000

35

The Uremic Toxin 3-Indoxyl Sulfate Is a Potent Endogenous Agonist for the Human Aryl Hydrocarbon Receptor

Schroeder, Jennifer C., DiNatale, Brett C., Murray, Iain A., Flaveny, Colin A., Liu, Qiang, Laurenzana, Elizabeth M., Lin, Jyh Ming, Strom, Stephen C., Omiecinski, Curtis J., Amin, Shantu, Perdew, Gar

Journal:

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

36

Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence

Hassett, Christopher, Richter, Rebecca J., Humbert, Richard, Chapline, Christine, Crabb, John W., Omiecinski, Curtis J., Furlong, Clement E.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.79 MB

english, 1991

37

Δ 9 -Tetrahydrocannabinol Disrupts Estrogen-Signaling through Up-Regulation of Estrogen Receptor β (ERβ)

Takeda, Shuso, Yoshida, Kazutaka, Nishimura, Hajime, Harada, Mari, Okajima, Shunsuke, Miyoshi, Hiroko, Okamoto, Yoshiko, Amamoto, Toshiaki, Watanabe, Kazuhito, Omiecinski, Curtis J., Aramaki, Hironori

Journal:

Chemical Research in Toxicology

Year:

2013

Language:

english

File:

PDF, 3.31 MB

english, 2013

38

Sp1 and Sp3 transcription factors regulate the basal expression of human microsomal epoxide hydrolase (EPHX1) through interaction with the E1b far upstream promoter

Su, Shengzhong, Omiecinski, Curtis J.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

39

The human constitutive androstane receptor promotes the differentiation and maturation of hepatic-like cells

Chen, Fengming, Zamule, Stephanie M., Coslo, Denise M., Chen, Tao, Omiecinski, Curtis J.

Journal:

Developmental Biology

Year:

2013

Language:

english

File:

PDF, 1.87 MB

english, 2013

40

(−)-Xanthatin up-regulation of the GADD45γ tumor suppressor gene in MDA-MB-231 breast cancer cells: Role of topoisomerase IIα inhibition and reactive oxygen species

Takeda, Shuso, Noguchi, Momoko, Matsuo, Kazumasa, Yamaguchi, Yasuhiro, Kudo, Taichi, Nishimura, Hajime, Okamoto, Yoshiko, Amamoto, Toshiaki, Shindo, Mitsuru, Omiecinski, Curtis J., Aramaki, Hironori

Journal:

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

41

Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action

Currie, Richard A., Peffer, Richard C., Goetz, Amber K., Omiecinski, Curtis J., Goodman, Jay I.

Journal:

Year:

2014

Language:

english

File:

PDF, 892 KB

english, 2014

42

Intronic DNA elements regulate Nrf2 chemical responsiveness of the human microsomal epoxide hydrolase gene (EPHX1) through a far upstream alternative promoter

Su, Shengzhong, Yang, Xi, Omiecinski, Curtis J.

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

43

Assessment of Regional Cytochrome P450 Activities in Rat Liver Slices Using Resorufin Substrates and Fluorescence Confocal Laser Cytometry

John T. Heinonen, Jaspreet S. Sidhu, Maureen T. Reilly, Federico M. Farin, Curtis J. Omiecinski, David L. Eaton and Terrance J. Kavanagh

Journal:

Environmental Health Perspectives

Year:

1996

Language:

english

File:

PDF, 3.03 MB

english, 1996

44

(−)-Xanthatin Selectively Induces GADD45γ and Stimulates Caspase-Independent Cell Death in Human Breast Cancer MDA-MB-231 Cells

Takeda, Shuso, Matsuo, Kazumasa, Yaji, Kentaro, Okajima-Miyazaki, Shunsuke, Harada, Mari, Miyoshi, Hiroko, Okamoto, Yoshiko, Amamoto, Toshiaki, Shindo, Mitsuru, Omiecinski, Curtis J., Aramaki, Hironor

Journal:

Chemical Research in Toxicology

Year:

2011

Language:

english

File:

PDF, 3.44 MB

english, 2011

45

Hepatic Expression of Rat P450 mRNA Assessed by In Situ Hybridization to Oligomer Probes

HASSETT, CHRISTOPHER, LUCHTEL, DANIEL L., OMIECINSKI, CURTIS J.

Journal:

Year:

1989

Language:

english

File:

PDF, 12.49 MB

english, 1989

46

Quantification of Multiple Human Cytochrome P450 mRNA Molecules Using Competitive Reverse Transcriptase-PCR

ANDERSEN, MARK R., FARIN, FEDERICO M., OMIECINSKI, CURTIS J.

Journal:

DNA and Cell Biology

Year:

1998

Language:

english

File:

PDF, 491 KB

english, 1998

47

Tissue-specific expression of rat mRNAs homologous to cytochromes P-450b and P-450e

Omiecinski, Curtis J.

Journal:

Nucleic Acids Research

Year:

1986

Language:

english

File:

PDF, 1.99 MB

english, 1986

48

Sequence and gene expression of rabbit cytochrome P450 IIC16: comparison to highly related family members

Hassett, Christopher, Omiecinski, Curtis J.

Journal:

Nucleic Acids Research

Year:

1990

Language:

english

File:

PDF, 2.36 MB

english, 1990

49

Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor

Chen, Tao, Laurenzana, Elizabeth M., Coslo, Denise M., Chen, Fengming, Omiecinski, Curtis J.

Journal:

Biochemical Journal

Year:

2014

Language:

english

File:

PDF, 1.27 MB

english, 2014

50

Regiospecific expression of cytochrome P‐450s and microsomal epoxide hydrolase in human brain tissue

Farin, Federico M., Omiecinski, Curtis J.

Journal:

Journal of Toxicology and Environmental Health

Year:

1993

Language:

english

File:

PDF, 1.27 MB

english, 1993